Each week Collective IP highlights a particular profile, either a company, an investigator or technology transfer office. Today we shine the light upon the University California, Irvine.
The UCI Office of Technology Alliances (OTA) exists to foster faculty/industry alliances and commercialization of UC Irvine technology for the broad public benefit. OTA emphasizes accessibility, timeliness, and flexibility in its operations and negotiations to ensure that the federal, state and private investment in UCI research has the greatest possible positive impact on people and the economy.
At the end of fiscal year 2013 OTA managed:
- 938 inventions in its portfolio
- 359 active US patents
- 102 active license or option agreements
OTA has participated in founding more than 60 companies.
Is there a particular technology residing with your office/university you wish to highlight?
Researchers at UCI, in collaboration with colleagues at the Italian Institute of Technology in Italy, are developing novel small-molecule inhibitors of intracellular acid ceramidase activity. These compounds act at single digit nanomolar concentrations to sensitize tumor cells to current anticancer drugs and radiation therapy, increasing the potency of standard chemotherapies by 10-20 fold.
Novel Acid Ceramidase Inhibitors for Oncology and Neuropathic Pain
Tech ID: 24060 / UC Case 2013-225-0
Patent Status: Patent Pending
- Discovery of a New Class of Highly Potent Inhibitors of Acid Ceramidase: Synthesis and Structure–Activity Relationship (SAR). J. Med. Chem., 2013, 56(9):3518-3530 PubmedID: 23614460
- Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity. Sci Rep. 2013; 3: 1035. PubmedID: 23301156
Is there a particular faculty/student-inventor you would like to highlight?
Dr. Payam Heydari is currently a Professor of Electrical Engineering at the University of California, Irvine. He is also an IEEE Distinguished Lecturer. He received his B.S. and M.S. degrees (Honors) in Electrical Engineering from Sharif University of Technology in 1992 and 1995, respectively. He received his Ph.D. degree from the University of Southern California in 2001.
- Collective IP Profile – Payam Heydari
- UC Irvine Faculty Profile – Dr. Payam Heydari
- Dr. Payam Heydari – IEEE Distingushed Lecture Program
His IEEE Lectures are:
- Distributed Integrated Circuits for Broadband Communications
- “Millimeter-wave and Terahertz Integrated Circuits in Silicon Technologies: Challenges and Solutions”
- Millimeter-wave Imaging and Sensing in Silicon
- Terahertz and Millimeter-Wave Frequency Generation and Synthesis in Silicon.
Are there any spin-out start-up companies or licensee relationships associated with your office/university you wish to draw attention to?
SRCH2 is a company based upon UCI technology. The company and their programs were recently featured in the UC technology commercialization 2013 University of California Technology Commercialization Report.
SRCH2 was founded by Stanford PhDs and ex-Googlers, based on a decade of award-winning and patented research, funded by data industry insiders and top tier venture firms, built to address the search needs of modern data-driven applications. SRCH2’s in-memory search engine provides high performance and high efficiency at massive scale in one framework.
Are there any unique programs associated with your office you wish to highlight?
UCI Irvine has an extensive social media platform, including apps in the Apple, Google, and Kindle stores, online blog, website, YouTube channel, Dropbox and other technologies. We understand the importance of leveraging our extensive portfolio and management techniques to expand our contacts and developments. We are currently expanding our research capabilities to include projects in defense offset collaborations, leveraging our extensive international research programs in this field. We anticipate expanding these relationships further over the next few years.
Do you have any comments you would like to share about the Collective IP platform, and our efforts to organize the Innovation Ecosystem, and bring academia and industry together faster and more efficiently than ever before?
We think the Collective IP platform is an excellent way to get the message out on patenting, research, and clinical trials and demonstrate the full extent of UCI’s work. We have featured Collective IP in our app as a demonstration of our view of the effectiveness of the program.
UCI OTA Contacts:
Casie Kelly, Ph.D.
Senior Licensing Officer
UCI Office of Technology Alliances