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Publication
PubMed ID28098412Published Date2017-04-30JournalStatistics in medicine, 2017-04-30, Volume 36
Exposure to particulate matter (PM) air pollution has been associated with a range of adverse health outcomes, including cardiovascular disease hospitalizations and other clinical parameters. Determining which sources of PM, such as traffic or industry, are most associated with adverse health outcomes could help guide future recommendations aimed at reducing harmful pollution exposure for susceptible individuals. Information obtained from multisite studies, which is generally more precise tha…
Clinical Trial
Clinical Trial IDNCT03066050Start Date2017-05-01Completion Date0031-12-01PhaseN/AStudy TypeObservationalStatusNot yet recruiting
This study is a continuation of two previous studies --- the Severe Ischemic Mitral Regurgitation (SMR) Trial (NCT00807040) and the Moderate Ischemic Mitral regurgitation (MMR) Trial (NCT00806988) --- to learn more about patients' health 5-10 years after their mitral valve surgeries. The investigators will collect long-term health information on SMR and MMR trial participants using electronic medical records, patient and/or family input, public records, and healthcare- and vital status-relate…
Publication
PubMed ID28320899Published Date2017-04-28JournalPhilosophical transactions. Series A, Mathematical, physical, and engineering sciences, 2017-04-28, Volume 375
We report a new global potential energy surface (PES) for HCO, based on precise fitting of roughly 67 000 MRCI/cc-pVTZ energies. This PES describes the global minimum, the - and -HCOH isomers, and barriers relevant to isomerization, formation of the molecular (H+CO) and radical (H+HCO) products, and the loose so-called roaming transition-state saddle point. The key features of the PES are reviewed and compared with a previous PES, denoted by PES04, based on five local fits that are 'stitched'…
Clinical Trial
Clinical Trial IDNCT03008889Start Date2017-05-01Completion Date2019-12-01PhasePhase 2Study TypeInterventionalStatusNot yet recruiting
The purpose of this study is to demonstrate the feasibility of a 9-week, randomized trial of N-acetylcysteine (NAC) compared to placebo in 14 children (age 5 to 12 years) with Autism Spectrum Disorder (ASD) and a moderate level of repetitive self-injurious behavior (SIB). Additional aims are to evaluate the positive predictive value of a screening method to classify children with automatically maintained self-injurious behavior; to evaluate the preliminary efficacy of NAC for reducing repetit…
Publication
PubMed ID28372715Published Date2017-05-01JournalThe Medical clinics of North America, 2017-05-01, Volume 101
Diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) are the most serious and life-threatening hyperglycemic emergencies in diabetes. DKA is more common in young people with type 1 diabetes and HHS in adult and elderly patients with type 2 diabetes. Features of the 2 disorders with ketoacidosis and hyperosmolality may coexist. Both are characterized by insulinopenia and severe hyperglycemia. Early diagnosis and management are paramount. Treatment is aggressive rehydration, i…
Publication
PubMed ID28045711Published Date2017-05-01JournalEpidemiology (Cambridge, Mass.), 2017-05-01, Volume 28
Abstract not available
Publication
PubMed ID27595594Published Date2017-05-01JournalMolecular psychiatry, 2017-05-01, Volume 22
Positive affect denotes a state of pleasurable engagement with the environment eliciting positive emotion such as contentment, enthusiasm or happiness. Positive affect is associated with favorable psychological, physical and economic outcomes in many longitudinal studies. With a heritability of ⩽64%, positive affect is substantially influenced by genetic factors; however, our understanding of genetic pathways underlying individual differences in positive affect is still limited. Here, through…
Publication
PubMed ID28385804Published Date2017-05-01JournalAnnals of the rheumatic diseases, 2017-05-01, Volume 76
To develop response criteria for juvenile dermatomyositis (DM). We analysed the performance of 312 definitions that used core set measures from either the International Myositis Assessment and Clinical Studies Group (IMACS) or the Paediatric Rheumatology International Trials Organisation (PRINTO) and were derived from natural history data and a conjoint analysis survey. They were further validated using data from the PRINTO trial of prednisone alone compared to prednisone with methotrexate or…
Publication
PubMed ID27915483Published Date2017-05-01JournalAIDS care, 2017-05-01, Volume 29
This cross-sectional study sought to determine factors associated with sterilization among HIV-positive US women. HIV-positive women aged 18-45 completed an Audio Computer Assisted Self Interview (ACASI) questionnaire. Chi-square tests and multivariable logistic regression evaluated factors associated with sterilization. The median age of the 187 participants was 37, the majority had at least a high school education, and 88% were African American. Nearly a quarter (22%) of women had undergone…
Publication
PubMed ID28395846Published Date2017-05-01JournalThe Lancet. Global health, 2017-05-01, Volume 5
Although childhood trauma and violence against women are global public health issues, few population-based data from low-income and middle-income countries exist about the links between them. We present data from the UN Multi-country Study on Men and Violence in Asia and the Pacific, exploring the pathways between different forms of childhood trauma and violence against women.In this multicountry study, we interviewed multistage representative samples of men and women, aged 18-49 years, in As…