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Clinical Trial
Clinical Trial IDNCT02573896Start Date2017-06-01Completion Date2020-06-01PhasePhase 1Study TypeInterventionalStatusNot yet recruiting
This NANT trial will determine the maximum tolerated dose (MTD) of autologous expanded natural killer (NK) cells when combined with standard dosing of ch14.18 and will assess the feasibility of adding lenalidomide at the recommended Phase II dose of the expanded NK cells with ch14.18, for treatment of children with refractory or recurrent neuroblastoma.
Publication
PubMed ID28063166Published Date2017-06-01JournalInternational journal of cancer, 2017-06-01, Volume 140
Cigarette smoking is associated with an increased risk of developing mucinous ovarian tumors but whether it is associated with ovarian cancer survival overall or for the different histotypes is unestablished. Furthermore, it is unknown whether the association between cigarette smoking and survival differs according to strata of ovarian cancer stage at diagnosis. In a large pooled analysis, we evaluated the association between various measures of cigarette smoking and survival among women with…
Publication
PubMed ID28159360Published Date2017-06-01JournalInternational journal of cardiology, 2017-06-01, Volume 236
Abstract not available
Publication
PubMed ID28429423Published Date2017-06-01JournalThe Prostate, 2017-06-01, Volume 77
Abstract not available
Publication
PubMed ID26895152Published Date2017-06-01JournalJournal of immigrant and minority health, 2017-06-01, Volume 19
This study examined the effects of acculturation on anxiety and stress in Latino and non-Latino white parents of children undergoing outpatient surgery. Participants included 686 parent-child dyads from four major children's hospitals in the United States. Latino parents who grew up in the U.S. reported higher levels of anxiety (p = 0.009) and stress (p < 0.001) compared to parents who grew up in a Latin American country. Additionally, English-speaking Latino parents reported higher anxiety a…
Publication
PubMed ID28210538Published Date2017-06-01JournalPreventive medicine reports, 2017-06-01, Volume 6
Low dose CT (LDCT) for lung cancer screening is an evidence-based, guideline recommended, and Medicare approved test but uptake requires further study. We therefore conducted patient and provider surveys to elucidate factors associated with utilization. Patients referred for LDCT at an academic medical center were questioned about their attitudes, knowledge, and beliefs on lung cancer screening. Adherent patients were defined as those who met screening eligibility criteria and completed a LDC…
Publication
PubMed ID28280851Published Date2017-06-01JournalSkeletal radiology, 2017-06-01, Volume 46
To determine whether known variant anatomical relationships between the sciatic nerve and piriformis muscle can be identified on routine MRI studies of the hip and to establish their imaging prevalence.Hip MRI studies acquired over a period of 4 years at two medical centers underwent retrospective interpretation. Anatomical relationship between the sciatic nerve and the piriformis muscle was categorized according to the Beaton and Anson classification system. The presence of a split sciatic n…
Publication
PubMed ID28334358Published Date2017-06-01JournalJournal of biomechanical engineering, 2017-06-01, Volume 139
While abnormal loading is widely believed to cause cervical spine disc diseases, in vivo cervical disc deformation during dynamic neck motion has not been well delineated. This study investigated the range of cervical disc deformation during an in vivo functional flexion-extension of the neck. Ten asymptomatic human subjects were tested using a combined dual fluoroscopic imaging system (DFIS) and magnetic resonance imaging (MRI)-based three-dimensional (3D) modeling technique. Overall disc de…
Publication
PubMed ID28079556Published Date2017-06-01JournalClinical obstetrics and gynecology, 2017-06-01, Volume 60
In contrast with other high-resource countries, maternal mortality has seen an increase in the United States. Caring for pregnant women in cardiac arrest may prove uniquely challenging given the rarity of the event coupled by the physiological changes of pregnancy. Optimization of resuscitative efforts warrants special attention as described in the 2015 American Heart Association's "Scientific Statement on Maternal Cardiac Arrest." Current recommendations address a variety of topics ranging f…
Publication
PubMed ID28342321Published Date2017-06-01JournalBiomaterials, 2017-06-01, Volume 129
The Caco-2 assay has achieved wide popularity among pharmaceutical companies in the past two decades as an in vitro method for estimation of in vivo oral bioavailability of pharmaceutical compounds during preclinical characterization. Despite its popularity, this assay suffers from a severe underprediction of the transport of drugs which are absorbed paracellularly, that is, which pass through the cell-cell tight junctions of the absorptive cells of the small intestine. Here, we propose that …