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Clinical Trial
Clinical Trial IDNCT03116230Start Date2017-07-01Completion Date2019-06-01PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
The objective of this study is complete a longitudinal cross-over clinical study to investigate the effect of treatments for knee pathology, including cutaneous stimulation (skin vibration and soft knee brace), on locomotion tasks (i.e. walking, jogging, stair ascending and descending), muscle function, and pain/function.
Publication
PubMed ID27868471Published Date2017-07-01JournalLeukemia & lymphoma, 2017-07-01, Volume 58
This phase 2 study evaluated brentuximab vedotin monotherapy in CD30-expressing DLBCL; after several patients with little to no CD30 achieved a complete remission (CR), the study evaluated treatment of DLBCL with undetectable CD30 (CD30u) by local visual immunohistochemistry (vIHC). Sixteen of 52 CD30u DLBCL patients (31%) had an objective response (6 CRs [12%]). Median progression-free survival (PFS) was 1.4 months (range, 0.4-15.6) and median overall survival (OS) was 7.5 months (range, 0.7…
Publication
PubMed ID28364689Published Date2017-07-05JournalJournal of hazardous materials, 2017-07-05, Volume 333
Natural products are becoming increasingly popular in multiple fields involving medicines, foods and beverages. However, due to the frequent occurrence of poisoning incidents, their toxicity and safety have caused a serious concern. Here we report a method of biosensor-based two-phase pharmacological profiling (BTPP) for discovery, monitor and control of receptor-targeted natural products. BTPP uses a resonant waveguide grating biosensor for label-free and non-invasive detection of intracellu…
Publication
PubMed ID27815005Published Date2017-06-15JournalJournal of environmental management, 2017-06-15, Volume 195
We analyze the impacts of investments in sustainable land use practices on ecosystem services in the Upper Tana basin, Kenya. This work supports implementation of the Upper Tana-Nairobi Water Fund, a public-private partnership to safeguard ecosystem service provision and food security. We apply an integrated modelling framework, building on local knowledge and previous field- and model-based studies, to link biophysical landscape changes at high temporal and spatial resolution to economic ben…
Publication
PubMed ID27650710Published Date2017-07-15JournalBiosensors & bioelectronics, 2017-07-15, Volume 93
Microarrays and other surface-based nucleic acid detection schemes rely on the hybridization of the target to surface-bound detection probes. We present the first comparison of two strategies to detect DNA using a giant magnetoresistive (GMR) biosensor platform starting from an initially double-stranded DNA target. The target strand of interest is biotinylated and detected by the GMR sensor by linking streptavidin magnetic nanoparticles (MNPs) to the sensor surface. The sensor platform has a …
Publication
PubMed ID28063166Published Date2017-06-01JournalInternational journal of cancer, 2017-06-01, Volume 140
Cigarette smoking is associated with an increased risk of developing mucinous ovarian tumors but whether it is associated with ovarian cancer survival overall or for the different histotypes is unestablished. Furthermore, it is unknown whether the association between cigarette smoking and survival differs according to strata of ovarian cancer stage at diagnosis. In a large pooled analysis, we evaluated the association between various measures of cigarette smoking and survival among women with…
Publication
PubMed ID28159360Published Date2017-06-01JournalInternational journal of cardiology, 2017-06-01, Volume 236
Abstract not available
Publication
PubMed ID28429423Published Date2017-06-01JournalThe Prostate, 2017-06-01, Volume 77
Abstract not available
Publication
PubMed ID26895152Published Date2017-06-01JournalJournal of immigrant and minority health, 2017-06-01, Volume 19
This study examined the effects of acculturation on anxiety and stress in Latino and non-Latino white parents of children undergoing outpatient surgery. Participants included 686 parent-child dyads from four major children's hospitals in the United States. Latino parents who grew up in the U.S. reported higher levels of anxiety (p = 0.009) and stress (p < 0.001) compared to parents who grew up in a Latin American country. Additionally, English-speaking Latino parents reported higher anxiety a…