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Publication
PubMed ID28358297Published Date2017-05-01JournalExperimental aging research, 2017-05-01, Volume 43
Background/Study Context: Aging research addressing spatial learning, representation, and action is almost exclusively based on vision as the input source. Much less is known about how spatial abilities from nonvisual inputs, particularly from haptic information, may change during life-span spatial development. This research studied whether learning and updating of haptic target configurations differs as a function of age.Three groups of participants, ranging from 20 to 80 years old, felt fou…
Publication
PubMed ID27859942Published Date2017-05-01JournalGlobal change biology, 2017-05-01, Volume 23
Numerous studies have demonstrated that soil respiration rates increase under experimental warming, although the long-term, multiyear dynamics of this feedback are not well constrained. Less is known about the effects of single, punctuated events in combination with other longer-duration anthropogenic influences on the dynamics of soil carbon (C) loss. In 2012 and 2013, we assessed the effects of decadal-scale anthropogenic global change - warming, increased nitrogen (N) deposition, elevated …
Publication
PubMed ID28422574Published Date2017-04-19JournalArchives of suicide research : official journal of the International Academy for Suicide Research, 2017-04-19
Joiner's interpersonal psychological theory of suicide (IPTS) is predated by literature examining maladaptive interpersonal behaviors associated with depression; however, research has not examined the potential relevance of such behaviors for the IPTS. The current study aimed to expand understanding of suicide risk by examining two maladaptive interpersonal behaviors in the context of Joiner's IPTS model.Structural equation modeling examined associations between depressive symptoms, social-co…
Patent
Publication NumberEP 2539456 B1StatusIssued PatentAvailabilityUnknownFiling Date2011-02-28Publication Date2017-04-19
Publication
PubMed ID28413999Published Date2017-04-17JournalJournal of the International Neuropsychological Society : JINS, 2017-04-17
Longitudinal research indicates that cognitive load dual-task gait assessment is predictive of cognitive decline and thus might provide a sensitive measure to screen for mild cognitive impairment (MCI). However, research among older adults being clinically evaluated for cognitive concerns, a defining feature of MCI, is lacking. The present study investigated the effect of performing a cognitive task on normal walking speed in patients presenting to a memory clinic with cognitive complaints.Si…
Publication
PubMed ID28402387Published Date2017-04-11JournalAmerican journal of hypertension, 2017-04-11
Abstract not available
Publication
PubMed ID28411036Published Date2017-04-11JournalToxicology and applied pharmacology, 2017-04-11
Chromosome instability is a common feature of cancers that forms due to the misrepair of DNA double strand breaks. Homologous recombination (HR) repair is a high fidelity DNA repair pathway that utilizes a homologous DNA sequence to accurately repair such damage and protect the genome. Prolonged exposure (>72h) to the human lung carcinogen, particulate hexavalent chromium (Cr(VI)), inhibits HR repair, resulting in increased chromosome instability in human cells. Comparative studies have shown…
Publication
PubMed ID28408238Published Date2017-04-10JournalExperimental hematology, 2017-04-10
Podocalyxin (Podxl) is a CD34 orthologue and cell surface sialomucin with reported roles in renal podocyte diaphragm slit development, vascular cell integrity, and the progression of blood, breast, and prostate cancers. Roles for Podxl during non-malignant hematopoiesis, however, are largely undefined. Presently we have developed a Vav-Cre Podxl knockout mouse model, and report on novel roles for Podxl in governing stress myelopoiesis. At steady-state, Podxl expression among hematopoietic pro…
Publication
PubMed ID28396125Published Date2017-04-08JournalJournal of theoretical biology, 2017-04-08, Volume 422
Biological networks, like most engineered networks, are not the product of a singular design but rather are the result of a long process of refinement and optimization. Many large real-world networks are comprised of well-defined and meaningful smaller modules. While engineered networks are designed and refined by humans with particular goals in mind, biological networks are created by the selective pressures of evolution. In this paper, we seek to define aspects of network architecture that …
Publication
PubMed ID28122195Published Date2017-04-07JournalJournal of theoretical biology, 2017-04-07, Volume 418
Beginning in 2001, many instances of malicious software known as Internet worms have been using biological strategies such as hierarchical dispersal to seek out and spread to new susceptible hosts more efficiently. We measured the distribution of potentially susceptible hosts in the space of Internet addresses to determine their clustering. We have used the results to construct a full-size simulated Internet with 2 hosts with mean and variance of susceptible hosts chosen to match our measurem…