1750
1750
1784
1784
1824
1824
1916
1916
1877
1877
2007
2007
2063
2063
2168
2168
2284
2284
2513
2513
2621
2621
2958
2958
3006
3006
3776
3776
3792
3792
3981
3981
4154
4154
5206
5206
6029
6029
7100
7100
2016
1995
1 - 10 of 83,450
Sort by
Clinical Trial
Clinical Trial IDNCT03016689Start Date2017-03-01Completion Date2021-01-01PhaseN/AStudy TypeObservationalStatusNot yet recruiting
While the maternal-newborn exchange of airway microbiota is well-documented, no studies have examined within-subject relationships among the mouth, sinuses, nasopharynx and lungs and the relative abundance of bacterial taxa at those sites. Recent evidence suggests the oral cavity may serve as a reservoir for pathogens that translocate to non-oral locations; oral-associated microbes infect most other body sites as evidence by 16S sequencing. By using a combination of oral and throat swabs, tog…
Clinical Trial
Clinical Trial IDNCT03019666Start Date2017-03-01Completion Date2019-03-01PhasePhase 1Study TypeInterventionalStatusNot yet recruiting
This is a phase I trial with pilot expansion of HLA-haploidentical or HLA-mismatched related donor nicotinamide expanded-natural killer (NAM-NK) cell based therapy for patients with relapsed or refractory multiple myeloma (MM) or relapsed/refractory CD20-positive non-Hodgkin lymphoma (NHL). The primary endpoint of the study is to determine the maximum tolerated dose (MTD) of NAM-NK cells while maintaining safety.
Clinical Trial
Clinical Trial IDNCT02661035Start Date2017-03-01Completion Date2023-03-01PhasePhase 2Study TypeInterventionalStatusNot yet recruiting
This is a phase II trial using a non-myeloablative cyclophosphamide/ fludarabine/total body irradiation (TBI) preparative regimen followed by a related or unrelated donor stem cell infusion. The primary objective is to evaluate rates of acute graft-versus-host disease (GVHD) grades II-IV and chronic GVHD with an updated GVHD prophylaxis of tacrolimus and mycophenolate mofetil (MMF) with a non-myeloablative preparative regimen in persons with hematologic malignancies.
Clinical Trial
Clinical Trial IDNCT02636283Start Date2017-03-01Completion Date2019-05-01PhasePhase 2Study TypeInterventionalStatusNot yet recruiting
This study proposes the use of Entresto (sacubitril/valsartan) to test the effects on pain free walking duration on patients with peripheral arterial disease, a condition caused by decreased blood flow to the muscles in the legs.
Clinical Trial
Clinical Trial IDNCT02954042Start Date2017-03-01Completion Date2018-12-01PhasePhase 2Study TypeInterventionalStatusNot yet recruiting
The purpose of this investigation is to compare the clinical benefits of using the Pelvital product, in comparison to a sham procedure as a noninvasive treatment for female incontinence
Clinical Trial
Clinical Trial IDNCT03002012Start Date2017-03-01Completion Date2021-10-01PhasePhase 3Study TypeInterventionalStatusNot yet recruiting
Cryptococcal meningitis or "Crypto" is a life threatening fungal infection around the brain that requires hospitalization for treatment for 14 days and then continued therapy. Crypto causes 15-20% of HIV/AIDS-related deaths worldwide. However, this infection can be detected before one develops symptoms and becomes ill. People can be screened for infection by a blood test to detect "cryptococcal antigen," (called CrAg), which is part of the fungus, in blood. The World Health Organization and o…
Clinical Trial
Clinical Trial IDNCT02959645Start Date2017-03-01Completion Date2018-07-01PhaseN/AStudy TypeObservational [Patient Registry]StatusNot yet recruiting
To address joint position sense in cervical dystonia patients and how it affects the brain activity.
Publication
PubMed ID26274936Published Date2017-03-01JournalInternational journal of injury control and safety promotion, 2017-03-01, Volume 24
Individuals with high levels of hostility may be more susceptible to the influence of television on violence and risk taking behaviors. This study aimed to examine whether hostile personality trait modifies the association between TV viewing and injuries. It is a prospective study of 4,196 black and white adults aged 23 to 35 in 1990/1. Cross-lagged panel models were analyzed at three 5-year time periods to test whether TV viewing predicted injuries. Covariates were gender, race, and educatio…
Publication
PubMed ID27939288Published Date2017-03-01JournalDiagnostic microbiology and infectious disease, 2017-03-01, Volume 87
The objective of this study was to evaluate molecular and epidemiologic factors associated with Escherichia coli sequence type 131 (ST131) among long-term care facility (LTCF) residents who acquired gastrointestinal tract colonization with fluoroquinolone-resistant E. coli (FQREC). Colonizing isolates from 37 residents who newly developed FQREC colonization at three LTCFs from 2006 to 2008 were evaluated. Twenty-nine (78%) of 37 total FQREC colonizing isolates were ST131. Most ST131 isolates …
Publication
PubMed ID27717291Published Date2017-03-01JournalJournal of occupational and environmental hygiene, 2017-03-01, Volume 14
The use of the turbulent eddy diffusion model and its variants in exposure assessment is limited due to the lack of knowledge regarding the isotropic eddy diffusion coefficient, D. But some studies have suggested a possible relationship between D and the air changes per hour (ACH) through a room. The main goal of this study was to accurately estimate D for a range of ACH values by minimizing the difference between the concentrations measured and predicted by eddy diffusion model. We construct…